St. Paul's is designated by English Heritage as a Grade II listed building.
A chapel was first built in Skelmersdale in 1776 as a chapel of ease for St Peter and St Paul, Ormskirk. It was enlarged in 1823 and again in 1850. In 1856 it became a parish church in its own right and was dedicated to Saint Paul. The foundation stone for the present church was laid in 1903 and the church was consecrated on 18th December 1906.